1,2-(2H4)Ethanediol

Names

[ Name ]:
1,2-(2H4)Ethanediol

[Synonym ]:
1,2-(H)Ethanediol
d2-hydrogen sulphide
deuterium-labeled ethylene glycol
(H)Ethane-1,2-diol
ethylene glycol-d6
EINECS 218-730-5
MFCD00075388
Hydrogen sulfide-d2
1,2-Ethane-d-diol
Ethylene-d4Glycol

Biological Activity

[Description]:

Ethylene glycol-d4 is the deuterium labeled Ethylene glycol[1].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
197.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-13ºC(lit.)

[ Molecular Formula ]:
C₂H₂D₄O₂

[ Molecular Weight ]:
66.092

[ Flash Point ]:
108.2±13.0 °C

[ Exact Mass ]:
66.061890

[ PSA ]:
40.46000

[ LogP ]:
-1.69

[ Vapour Pressure ]:
0.1±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.422

[ Storage condition ]:
2-8°C

MSDS

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Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S2

[ RIDADR ]:
UN 3082 9 / PGIII

[ WGK Germany ]:
3

[ HS Code ]:
2905310000

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2905310000

[ Summary ]:
HS:2905310000 ethane-1,2-diol VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%