Compound 621433144
Names
[ CAS No. ]:
2223169-38-6
[ Name ]:
Compound 621433144
Biological Activity
[Description]:
Compound 621433144 (ZINC000621433144, Z3269026405) is a potent, selective full agonist of the D4 receptor with 2,500-fold subtype selectivity; Compound 621433144 was also functionally selective, with a 17-fold bias towards Gi signalling versus β-arrestin recruitment, compared to the characteristic agonist quinpirole.
[References]
References 1. Lyu J, et al. Nature. 2019 Feb 6. doi: 10.1038/s41586-019-0917-9. View Related Products by Target Dopamine Receptor
Chemical & Physical Properties
[ Molecular Formula ]:
C18H27N3O
[ Molecular Weight ]:
301.434