YTX-465

Names

[ Name ]:
YTX-465

Biological Activity

[Description]:

YTX-465 (YTX465) is a specific small molecule that rescues yeast from a-Syn cytotoxicity with EC50 of 15 nM, via inhibiting Ole1, the yeast homolog of human stearoyl-CoA desaturase (SCD); YTX-465 is inactive at SCD1.

[References]

References 1. Vincent BM, et al. Cell Rep. 2018 Dec 4;25(10):2742-2754.e31. View Related Products by Target Stearoyl-CoA Desaturase (SCD)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₆N₆O₃

[ Molecular Weight ]:
458.522

Related Compounds

disodium [[[[3-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]-4-sulphophenyl]amino]sulphonyl]sulphamoyl-29H,31H-phthalocyaninesulphonato(4-)-N29,N30,N31,N32]cuprate(2-)
Cellobiohydrolase I
aluminum,4-methylbenzenesulfonate
acid yellow 38
Labdanum, Me ester
Alkenes, C16-18, chlorosulfurized
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
Methyl 4-[(1,3-dihydrofuro[3,4-b]quinolin-9-yl)methyl]benzoate
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide