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BI-1408

Names

[ CAS No. ]:
2231075-94-6

[ Name ]:
BI-1408

Biological Activity

[Description]:

BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[Target]

IC50: 40 nM (Aβ42)[1]


[References]

[1]. Gerlach K, et al. Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators. Bioorg Med Chem. 2018 Jul 23;26(12):3227-3241.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H23FN6

[ Molecular Weight ]:
390.46

Related Compounds