Famprofazone
Names
[ CAS No. ]:
22881-35-2
[ Name ]:
Famprofazone
[Synonym ]:
Famprofazone
Famprofazona [INN-Spanish]
Famprofazonum [INN-Latin]
Chemical & Physical Properties
[ Density]:
1.083g/cm3
[ Boiling Point ]:
485.1ºC at 760mmHg
[ Molecular Formula ]:
C24H31N3O
[ Molecular Weight ]:
377.52200
[ Flash Point ]:
184.8ºC
[ Exact Mass ]:
377.24700
[ PSA ]:
30.17000
[ LogP ]:
4.36240
[ Vapour Pressure ]:
1.45E-09mmHg at 25°C
[ Index of Refraction ]:
1.574
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ9451000
- CHEMICAL NAME :
- Pyrazolin-5-one, 4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)m ethylamino)methyl-
- CAS REGISTRY NUMBER :
- 22881-35-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C24-H31-N3-O
- MOLECULAR WEIGHT :
- 377.58
- WISWESSER LINE NOTATION :
- T5NNVJ A1 BR& DY1&1 E1N1&Y1&1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- SMWOAS Schweizerische Medizinische Wochenschrift. (Schwabe & Co., Steintorst 13, 4010 Basel, Switzerland) V.50- 1920- Volume(issue)/page/year: 84,351,1954
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
22
[ Safety Phrases ]:
36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UQ9451000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Drug Metab. Rev. 32(1) , 15-44, (2000)
The interpretation of methamphetamine and amphetamine positive test results in biological samples is a challenge to clinical and forensic toxicology for several reasons. The effects of pH and dilution...
Detection and identification of famprofazone and its metabolite in human urine.J. Chromatogr. B, Biomed. Appl. 661(2) , 255-61, (1994)
Detection and identification of famprofazone and its metabolite, p-hydroxydesmethylfamprofazone, were described. The identity of the new metabolite was confirmed by comparing its mass spectrum and gas...
Urinary methamphetamine concentration following famprofazone administration.J. Anal. Toxicol. 18(5) , 265-8, (1994)
A 37-year-old man had a considerable concentration of methamphetamine in his urine, but he denied taking any abused drug. It was found that he took a pain killer that contains famprofazone, a relative...