indole-3-glyoxylyl chloride
Names
[ CAS No. ]:
22980-09-2
[ Name ]:
indole-3-glyoxylyl chloride
[Synonym ]:
MFCD00015460
2-indol-3-yl-2-oxoacetyl chloride
Indole-3-Glyoxylyl Chloride
Indole-3-glyoxyloyl chloride
EINECS 245-362-2
3-Indoleglyoxylyl chloride
3-indoleglyoxyl chloride
3-indolylglyoxalyl chloride
2-(3-indolyl)-2-oxo acetyl chloride
1h-indol-3-yl(oxo)acetyl chloride
Chemical & Physical Properties
[ Density]:
1.463 g/cm3
[ Boiling Point ]:
413.9ºC at 760 mmHg
[ Melting Point ]:
138 °C (dec.)(lit.)
[ Molecular Formula ]:
C10H6ClNO2
[ Molecular Weight ]:
207.61300
[ Flash Point ]:
204.1ºC
[ Exact Mass ]:
207.00900
[ PSA ]:
49.93000
[ LogP ]:
2.11600
[ Vapour Pressure ]:
4.63E-07mmHg at 25°C
[ Index of Refraction ]:
1.676
[ Storage condition ]:
2-8°C
MSDS
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C: Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S27-S36/37/39-S45
[ RIDADR ]:
UN 1759 8/PG 2
[ WGK Germany ]:
3
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
2918300090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Preparation
Customs
[ HS Code ]: 2918300090
[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Anal. Sci. 19(1) , 123-7, (2003)
The chemiluminescence (CL) intensities of various indole derivatives substituted with a glyoxylyl group at the 3-position and a hydroxyl group at the 5-position of the indole ring were compared upon t...
Notes-Concerning a preparation of tryptamine. Brutcher J, et al.J. Org. Chem. 23(1) , 146-147, (1958)
A concise synthesis of an AHR endogenous ligand with the indolecarbonylthiazole skeleton. Grzywacz P, et al.
Heterocycles 60(5) , 1219-1224, (2003)