γ Dodecalactone

Names

[ Name ]:
γ Dodecalactone

[Synonym ]:
γ-Dodecanolactone
EINECS 218-971-6
UNII:YX9N4581LU
FEMA 2400
G-DODECALACTONE
5-Octyldihydro-2(3H)-furanone
(±)-Dihydro-5-octyl-2(3H)-furanone
γ-Laurolactone
4-Decanolide
dodecalactone
MFCD00036499
4-Hydroxy-4-octylbutanoic acid lactone
5-Octyldihydrofuran-2(3H)-one
2(3H)-Furanone, dihydro-5-octyl-
4-Dodecanolide
Dodecanolide-1,4
4-Hydroxydodecanoic acid lactone
DODECANYL-LACTONE
g-Dodecanolactone
(±)-γ-Octyl-γ-butyrolactone
γ-Dodecalactone

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
294.7±8.0 °C at 760 mmHg

[ Melting Point ]:
17-18 °C(lit.)

[ Molecular Formula ]:
C₁₂H₂₂O₂

[ Molecular Weight ]:
198.302

[ Flash Point ]:
119.6±15.9 °C

[ Exact Mass ]:
198.161987

[ PSA ]:
26.30000

[ LogP ]:
3.45

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.451

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LU3600000

CHEMICAL NAME :: 2(3H)-Furanone, dihydro-5-octyl-

CAS REGISTRY NUMBER :: 2305-05-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H22-O2

MOLECULAR WEIGHT :: 198.34

WISWESSER LINE NOTATION :: T5OVTJ E8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,751,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7421 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
LU3600000

[ HS Code ]:
2932209090

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors.

J. Med. Chem. 48 , 3808-15, (2005)

The purpose of this study was to determine the cytochrome P450 1A2 (CYP1A2) inhibition potencies of structurally diverse compounds to create a comprehensive three-dimensional quantitative structure-ac...