PROTAC ERRα ligand 2

Names

[ Name ]:
PROTAC ERRα ligand 2

Biological Activity

[Description]:

PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist with an IC50 of 5.67 nM. PROTAC ERRα ligand 2 (IC50=5.67 nM) displays a ~11-fold improved potency than XCT790 (IC50=61.3 nM)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Estrogen Receptor/ERR

Research Areas >> Cancer

[References]

[1]. Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₃F₆NO₄

[ Molecular Weight ]:
445.31

PROTAC ERRα ligand 2

Names

Biological Activity

Chemical & Physical Properties

Related Compounds