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(S)-PI3Kα-IN-4

Names

[ CAS No. ]:
2322293-84-3

[ Name ]:
(S)-PI3Kα-IN-4

Biological Activity

[Description]:

(S)-PI3Kα-IN-4 is a potent inhibitor of PI3Kα, with an IC50 of 2.3 nM. (S)-PI3Kα-IN-4 shows 38.3-, 4.25-, and 4.93-fold selectivity for PI3Kα over PI3Kβ, PI3Kδ, and PI3Kγ, respectively. (S)-PI3Kα-IN-4 can be used for the research of cancer.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H23ClFN5O5S

[ Molecular Weight ]:
560.00


Related Compounds