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Urea,N-(2-chloroethyl)-N-nitroso-

Names

[ CAS No. ]:
2365-30-2

[ Name ]:
Urea,N-(2-chloroethyl)-N-nitroso-

[Synonym ]:
N-Chloroethyl-N-nitrosourea
N-Nitroso-2-chloraethylharnstoff
2-Chloroethyl-N-nitrosourea
Chloroethylnitrosourea
MP 655

Chemical & Physical Properties

[ Density]:
1.56g/cm3

[ Boiling Point ]:
241.2ºC at 760mmHg

[ Molecular Formula ]:
C3H6ClN3O2

[ Molecular Weight ]:
151.55200

[ Flash Point ]:
99.7ºC

[ Exact Mass ]:
151.01500

[ PSA ]:
75.76000

[ LogP ]:
0.98760

[ Vapour Pressure ]:
0.0364mmHg at 25°C

[ Index of Refraction ]:
1.566

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS5015000
CHEMICAL NAME :
Urea, 1-(2-chloroethyl)-1-nitroso-
CAS REGISTRY NUMBER :
2365-30-2
LAST UPDATED :
199612
DATA ITEMS CITED :
23
MOLECULAR FORMULA :
C3-H6-Cl-N3-O2
MOLECULAR WEIGHT :
151.57
WISWESSER LINE NOTATION :
ZVNNO&2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4368 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD10 - Lethal Dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4700 ug/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
10 mmol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,1887,1984

Safety Information

[ HS Code ]:
2924199090

Synthetic Route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds