Urea,N-(2-chloroethyl)-N-nitroso-
Names
[ CAS No. ]:
2365-30-2
[ Name ]:
Urea,N-(2-chloroethyl)-N-nitroso-
[Synonym ]:
N-Chloroethyl-N-nitrosourea
N-Nitroso-2-chloraethylharnstoff
2-Chloroethyl-N-nitrosourea
Chloroethylnitrosourea
MP 655
Chemical & Physical Properties
[ Density]:
1.56g/cm3
[ Boiling Point ]:
241.2ºC at 760mmHg
[ Molecular Formula ]:
C3H6ClN3O2
[ Molecular Weight ]:
151.55200
[ Flash Point ]:
99.7ºC
[ Exact Mass ]:
151.01500
[ PSA ]:
75.76000
[ LogP ]:
0.98760
[ Vapour Pressure ]:
0.0364mmHg at 25°C
[ Index of Refraction ]:
1.566
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS5015000
- CHEMICAL NAME :
- Urea, 1-(2-chloroethyl)-1-nitroso-
- CAS REGISTRY NUMBER :
- 2365-30-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 23
- MOLECULAR FORMULA :
- C3-H6-Cl-N3-O2
- MOLECULAR WEIGHT :
- 151.57
- WISWESSER LINE NOTATION :
- ZVNNO&2G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4368 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4700 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 10 mmol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,1887,1984
Safety Information
[ HS Code ]:
2924199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%