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cis VH 032

Names

[ CAS No. ]:
2376990-32-6

[ Name ]:
cis VH 032

[Synonym ]:
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4S)-, hydrochloride (1:2)
3-Methyl-L-valyl-(4S)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide dihydrochloride

Biological Activity

[Description]:

cis VH 032, amine dihydrochloride is a negative control for the functionalized VHL ligand VH 032, amine .

[References]

1. Kato JY, Korenaga S, Iwakura M. Discovery of a potent and subtype-selective TYK2 degrader based on an allosteric TYK2 inhibitor. Bioorg Med Chem Lett. 2023 Jan 1;79:129083.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H32Cl2N4O3S

[ Molecular Weight ]:
503.486

[ Exact Mass ]:
502.157227


Related Compounds