Perfluoro-tert-butanol

Names

[ Name ]:
Perfluoro-tert-butanol

[Synonym ]:
2,2,2-trifluoro-1,1-bis(trifluoromethyl)ethanol
Nonafluor-terc.butanol [Czech]
1,1,1,3,3,3-Hexafluoro-2-trifluoromethyl-2-propanol
Perfluoro-tert-butyl alcohol
1,1,1,3,3,3-Hexafluoro-2-(trifluoromethyl)-2-propanol
Nonafluoro-tert-butanol
EINECS 219-157-3
nonafluoro-tert-butyl alcohol
MFCD00042092
tris(trifluoromethyl)-tert-butanol
Perfluoro-tert-butanol

Chemical & Physical Properties

[ Density]:
1.693 g/mL at 25 °C(lit.)

[ Boiling Point ]:
45 °C(lit.)

[ Melting Point ]:
-17°C

[ Molecular Formula ]:
C₄HF₉O

[ Molecular Weight ]:
236.03600

[ Flash Point ]:
44-45°C

[ Exact Mass ]:
235.98800

[ PSA ]:
20.23000

[ LogP ]:
2.40440

[ Vapour Pressure ]:
45.7mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.3(lit.)

[ Storage condition ]:
Keep Cold

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB6452700

CHEMICAL NAME :: 2-Propanol, 1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)-

CAS REGISTRY NUMBER :: 2378-02-1

LAST UPDATED :: 199710

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C4-H-F9-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10230 mg/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,521,1986

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xn,Xi,T

[ Risk Phrases ]:
R20

[ Safety Phrases ]:
S26-S45-S36/37

[ RIDADR ]:
UN 2810 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
UB6452700

[ HS Code ]:
2905590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2905590090

[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Greener fluorous chemistry: Convenient preparation of new types of 'CF 3-rich'secondary alkyl mesylates and their use for the synthesis of azides, amines, imidazoles and imidazolium salts Nemes A, et al.

J. Fluor. Chem. 131(12) , 1368-76, (2010)

Cyclization and rearrangement products from coupling reactions between terminal o-alkynylphenols or o-ethynyl (hydroxymethyl) benzene and 6-halopurines. Berg TC, et al.

Tetrahedron 62(25) , 6121-31, (2006)