M-MoDE-A (2)

Names

[ Name ]:
M-MoDE-A (2)

Biological Activity

[Description]:

M-MoDE-A (2) is a bifunctional small molecule that mediates the degradation of extracellular proteins through the asialoglycoprotein receptor (ASGPR).

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Caianiello DF, et al. Bifunctional small molecules that mediate the degradation of extracellular proteins. Nat Chem Biol. 2021 Sep;17(9):947-953.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₈H₁₁₉FN₁₂O₃₄

[ Molecular Weight ]:
1787.84

Related Compounds

3-[[9-[3-carboxy-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]anilino]-9-oxononanoyl]amino]-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]benzoic acid
3-[[7-[3-carboxy-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]anilino]-7-oxoheptanoyl]amino]-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]benzoic acid
m-(2-phenoxyethoxy)phenol
m-((2-Methylpentanoyl)amino)phenyl tert-butylcarbamate
2-Pyridineethanol, a-(2-nitrophenyl)-
Benzenebutanoic acid, a,2,5-trimethyl-g-oxo-
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2,5-dioxopyrrolidin-1-yl (4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexane-1-carbonyl)glycylglycylglycinate
5-cyano-4-(4-methoxyphenyl)-N,N,2-trimethyl-6-sulfanylidenepiperidine-3-carboxamide
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
3-(2-Chloro-6-methylpyridin-4-yl)-3-fluoropropan-1-amine
tert-butyl N-{4-[1-(bromomethyl)cyclobutyl]butyl}carbamate