6-Oxabicyclo[3.1.0]hexane,2,2'-oxybis-

Names

[ Name ]:
6-Oxabicyclo[3.1.0]hexane,2,2'-oxybis-

[Synonym ]:
2,2'-oxybis-6-oxabicyclo[3.1.0]hexane
1,1'-Oxybis(2,3-epoxycyclopentane)
Bis-(2.3-epoxy-cyclopentyl)-aether
Ether,bis(2,3-epoxycyclopentyl)
EP-205
ERR 4205
EINECS 219-209-5
bis-(2,3-epoxycyclopentyl)-ether

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
281.6ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₄O₃

[ Molecular Weight ]:
182.21600

[ Flash Point ]:
93.2ºC

[ Exact Mass ]:
182.09400

[ PSA ]:
34.29000

[ LogP ]:
0.86260

[ Vapour Pressure ]:
0.00601mmHg at 25°C

[ Index of Refraction ]:
1.553

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RN9100000

CHEMICAL NAME :: 6-Oxabicyclo(3.1.0)hexane, 2,2'-oxybis-

CAS REGISTRY NUMBER :: 2386-90-5

LAST UPDATED :: 199710

DATA ITEMS CITED :: 16

MOLECULAR FORMULA :: C10-H14-O3

MOLECULAR WEIGHT :: 182.24

WISWESSER LINE NOTATION :: T35 BOTJ DO- DT35 BOTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2140 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - coma Vascular - shock

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 260 mg/m3/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 156 gm/kg/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 312 gm/kg/2Y-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors Reproductive - Tumorigenic effects - ovarian tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 395 gm/kg/132W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

REFERENCE :: CIHPDR Zhongguo Yixue Kexueyuan Xuebao. Journal of the Chinese Academy of Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1979- Volume(issue)/page/year: 6,210,1984 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 47,231,1989 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 47,231,1989

Safety Information

[ HS Code ]:
2932999099

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%