EV-A71-IN-1
Names
[ CAS No. ]:
2413648-96-9
[ Name ]:
EV-A71-IN-1
Biological Activity
[Description]:
EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM)[1].
[Related Catalog]:
[In Vitro]
EV-A71-IN-1 (compound 12s) shows activity not only against different EV-A71 strains (BrCr, GZ-CII, EV71/HeN09 and EV71/G082) but also against other representative enteroviruses (CV-A16, EV-D68, Echov-6, CV-B2 and CV-B6)[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C21H15N5S
[ Molecular Weight ]:
369.44