Butyl glycidyl ether
Names
[ CAS No. ]:
2426-08-6
[ Name ]:
Butyl glycidyl ether
[Synonym ]:
erl0810
BGE
Epirez 501
1-butoxy-2,3-epoxypropane
Heloxy 61
1,2-Epoxy-3-butoxypropane
ageflexbge
butyl 2,3-epoxypropyl ether
(Butoxymethyl)oxirane
2,3-epoxypropyl n-butyl ether
sipomerbge
MFCD00005145
2-(Butoxymethyl)oxirane
n-butyl glycidyl ether
EINECS 219-376-4
NBGE
Oxirane, 2-(butoxymethyl)-
3-n-butoxy-1,2-epoxypropane
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
177.0±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C7H14O2
[ Molecular Weight ]:
130.185
[ Flash Point ]:
54.4±0.0 °C
[ Exact Mass ]:
130.099380
[ PSA ]:
21.76000
[ LogP ]:
1.42
[ Vapour Pressure ]:
1.4±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.433
[ Stability ]:
Stable. May form explosive peroxides on contact with air. Store under inert gas.
[ Water Solubility ]:
2 g/100 mL
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX4200000
- CHEMICAL NAME :
- Propane, 1-butoxy-2,3-epoxy-
- CAS REGISTRY NUMBER :
- 2426-08-6
- BEILSTEIN REFERENCE NO. :
- 0103668
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 50
- MOLECULAR FORMULA :
- C7-H14-O2
- MOLECULAR WEIGHT :
- 130.21
- WISWESSER LINE NOTATION :
- T3OTJ B1O4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1660 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1030 ppm/8H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1140 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1530 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 260 mg/m3
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2520 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- DOSE :
- 36 gm/kg
- SEX/DURATION :
- male 24 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 249,55,1991 *** REVIEWS *** ACGIH TLV-TWA 133 mg/m3 (25 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 50 ppm (270 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,33,1971 OSHA PEL (Gen Indu):8H TWA 50 ppm (270 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 50 ppm (270 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 50 ppm (270 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 50 ppm (270 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 25 ppm (135 mg/m3) JAN 1993 OEL-BELGIUM:TWA 25 ppm (133 mg/m3) JAN 1993 OEL-DENMARK:TWA 6 ppm (30 mg/m3) JAN 1993 OEL-FINLAND:STEL 25 ppm (135 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 25 ppm (135 mg/m3) JAN 1993 OEL-GERMANY;Skin;Carcinogen JAN 1993 OEL-THE NETHERLANDS:TWA 25 ppm (135 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 50 ppm (270 mg/m3) JAN 1993 OEL-SWEDEN:TWA 10 ppm (50 mg/m3);STEL 15 ppm (80 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 25 ppm (135 mg/m3);STEL 50 ppm;Skin JAN 1993 OEL-TURKEY:TWA 50 ppm (270 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 25 ppm (135 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO BUTYL GLYCIDYL ETHER-air:CL 5.6 ppm/15M REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 14720 No. of Facilities: 1596 (estimated) No. of Industries: 37 No. of Occupations: 45 No. of Employees: 19839 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 14720 No. of Facilities: 2593 (estimated) No. of Industries: 56 No. of Occupations: 57 No. of Employees: 60217 (estimated) No. of Female Employees: 14929 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS05, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H302-H314-H317-H331-H335-H341-H350-H412
[ Precautionary Statements ]:
P201-P261-P273-P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R10;R20/22;R37;R40;R43;R52/53;R68
[ Safety Phrases ]:
S24/25-S36/37-S61
[ RIDADR ]:
UN 3271 3/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
TX4200000
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
29109000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2910900090
[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
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