Bafisontamab

Names

[ CAS No. ]:
2437210-79-0

[ Name ]:
Bafisontamab

[Description]:

Bafisontamab (EMB-01) is a bispecific antibody targeting EGFR and cMET with antitumor activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Met/HGFR

[Target]

EGFR

c-Met

[In Vivo]

Bafisontamab (EMB-01) 在 PDX 和 CDX 肿瘤模型中诱导的抗肿瘤活性明显强于抗 EGFR 单抗或抗 cMet 单抗。Bafisontamab 在抗 EGFR mAb 耐药肿瘤模型中表现出显著的抗肿瘤活性[1]。

[References]

No Any Chemical & Physical Properties