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Normeperidine hydrochloride (Norpethidine)

Names

[ CAS No. ]:
24465-45-0

[ Name ]:
Normeperidine hydrochloride (Norpethidine)

[Synonym ]:
4-Phenyl-piperidine-4-carboxylic acid ethyl ester hydrochloride
4-PIPERIDINECARBOXYLIC ACID,4-PHENYL-,ETHYL ESTER HYDROCHLORIDE
4-Carboethoxy-4-phenylpiperidine hydrochloride
4-PHENYL-4-CARBETHOXY PIPERIDINE HCL
4-CARBOETHOXY-4-PHENYLPIPERIDINE HCL
ethyl 4-phenylpiperidine-4-carboxylate hydrochloride
4-Phenyl-piperidin-4-carbonsaeure-aethylester,Hydrochlorid
isonipecoticacid,4-phenyl-,ethylester,hydrochloride
ethyl 4-phenyl-4-piperidinecarboxylate HCl
Normeperidine hydrochloride
ethyl 4-phenyl-4-piperidinecarboxylate hydrochloride
normepiridinehydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
333.5ºC at 760 mmHg

[ Molecular Formula ]:
C14H20ClNO2

[ Molecular Weight ]:
269.76700

[ Flash Point ]:
155.5ºC

[ Exact Mass ]:
269.11800

[ PSA ]:
38.33000

[ LogP ]:
3.00170

[ Vapour Pressure ]:
0.000136mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NS6195000
CHEMICAL NAME :
Isonipecotic acid, 4-phenyl-, ethyl ester, hydrochloride
CAS REGISTRY NUMBER :
24465-45-0
LAST UPDATED :
199012
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H19-N-O2.Cl-H
MOLECULAR WEIGHT :
269.80
WISWESSER LINE NOTATION :
T6MTJ DVO2 DR &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
84 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 112,191,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
63 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#12033

Safety Information

[ Hazard Codes ]:
F: Flammable;T: Toxic;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
7-16-36/37-45

[ RIDADR ]:
UN 1230 3/PG 2

[ HS Code ]:
2933399090

Synthetic Route

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds