Normeperidine hydrochloride (Norpethidine)
Names
[ CAS No. ]:
24465-45-0
[ Name ]:
Normeperidine hydrochloride (Norpethidine)
[Synonym ]:
4-Phenyl-piperidine-4-carboxylic acid ethyl ester hydrochloride
4-PIPERIDINECARBOXYLIC ACID,4-PHENYL-,ETHYL ESTER HYDROCHLORIDE
4-Carboethoxy-4-phenylpiperidine hydrochloride
4-PHENYL-4-CARBETHOXY PIPERIDINE HCL
4-CARBOETHOXY-4-PHENYLPIPERIDINE HCL
ethyl 4-phenylpiperidine-4-carboxylate hydrochloride
4-Phenyl-piperidin-4-carbonsaeure-aethylester,Hydrochlorid
isonipecoticacid,4-phenyl-,ethylester,hydrochloride
ethyl 4-phenyl-4-piperidinecarboxylate HCl
Normeperidine hydrochloride
ethyl 4-phenyl-4-piperidinecarboxylate hydrochloride
normepiridinehydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
333.5ºC at 760 mmHg
[ Molecular Formula ]:
C14H20ClNO2
[ Molecular Weight ]:
269.76700
[ Flash Point ]:
155.5ºC
[ Exact Mass ]:
269.11800
[ PSA ]:
38.33000
[ LogP ]:
3.00170
[ Vapour Pressure ]:
0.000136mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NS6195000
- CHEMICAL NAME :
- Isonipecotic acid, 4-phenyl-, ethyl ester, hydrochloride
- CAS REGISTRY NUMBER :
- 24465-45-0
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C14-H19-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 269.80
- WISWESSER LINE NOTATION :
- T6MTJ DVO2 DR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 84 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 112,191,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 63 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#12033
Safety Information
[ Hazard Codes ]:
F: Flammable;T: Toxic;
[ Risk Phrases ]:
R11
[ Safety Phrases ]:
7-16-36/37-45
[ RIDADR ]:
UN 1230 3/PG 2
[ HS Code ]:
2933399090
Synthetic Route
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%