rac cis-9,10-Epoxystearic Acid

Names

[ Name ]:
rac cis-9,10-Epoxystearic Acid

[Synonym ]:
dl-cis-9,10-epoxyoctadecanoic acid
AJ-76
cis-9,10-epoxyoctadecanoic acid

Biological Activity

[Description]:

cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) is an endogenous constituent in human blood and urine. cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) can be produced from oleic acid by enzymic and non-enzymic epoxidation[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Tsikas D, et al. Gas chromatography-mass spectrometry of cis-9,10-epoxyoctadecanoic acid (cis-EODA). II. Quantitative determination of cis-EODA in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 May 25;804(2):403-12.

Chemical & Physical Properties

[ Density]:
0.956g/cm3

[ Boiling Point ]:
422.9ºC at 760mmHg

[ Molecular Formula ]:
C₁₈H₃₄O₃

[ Molecular Weight ]:
298.46100

[ Flash Point ]:
141.1ºC

[ Exact Mass ]:
298.25100

[ PSA ]:
49.83000

[ LogP ]:
5.31970

[ Vapour Pressure ]:
2.46E-08mmHg at 25°C

[ Index of Refraction ]:
1.467

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RG1400000

CHEMICAL NAME :: Octadecanoic acid, 9,10-epoxy-, cis-

CAS REGISTRY NUMBER :: 24560-98-3

BEILSTEIN REFERENCE NO. :: 0085932

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H34-O3

MOLECULAR WEIGHT :: 298.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 164 mg/kg/41W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Tumorigenic - tumors at site of application

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 30,1037,1970

Safety Information

[ RTECS ]:
RG1400000

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%