Thalidomide-5-O-CH2-COOH

Names

[ Name ]:
Thalidomide-5-O-CH2-COOH

Biological Activity

[Description]:

Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₂N₂O₇

[ Molecular Weight ]:
332.26

Thalidomide-5-O-CH2-COOH

Names

Biological Activity

Chemical & Physical Properties

Related Compounds