Aβ-IN-3

Names

[ CAS No. ]:
2477606-87-2

[ Name ]:
Aβ-IN-3

Biological Activity

[Description]:

Aβ-IN-3 (compound 1) is a potent amyloid β (Aβ) inhibitor. Aβ-IN-3 inhibits Aβ42 aggregation. However, Aβ-IN-3 can not alleviate the neurotoxicity of Aβ42 in SH-SY5Y cells. Aβ-IN-3 can not change the aggregation state of Aβ42 into a nontoxic one[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Tanaka F, et al. Design and synthesis of β-strand-fixed peptides inhibiting aggregation of amyloid β-protein. Bioorg Med Chem. 2020 Sep 15;28(18):115676.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H43N5O7

[ Molecular Weight ]:
621.72

Related Compounds