Antileishmanial agent-9

Names

[ CAS No. ]:
2477608-91-4

[ Name ]:
Antileishmanial agent-9

Biological Activity

[Description]:

Antileishmanial agent-9 (compound 16c) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 4.01 μM. Antileishmanial agent-9 has relatively low cytotoxicity in L-6 cells (IC50 = 40.1 μM)[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

IC50: 4.01 μmol/L (L. donovani)[1]


[References]

[1]. Bernal FA, et al. (±)-trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis. Eur J Med Chem. 2020;205:112493.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H26O4

[ Molecular Weight ]:
366.45

Related Compounds