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FXIa-IN-7

Names

[ CAS No. ]:
2488952-56-1

[ Name ]:
FXIa-IN-7

Biological Activity

[Description]:

FXIa-IN-7 is a selective and orally bioavailable factor XIa inhibitor with an IC50 value of 0.4 nM.

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Factor Xa

[References]

[1]. Lorthiois E, et al. Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J Med Chem. 2020 Aug 13;63(15):8088-8113.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₂₈N₂O₄

[ Molecular Weight ]:
456.53

Related Compounds