sEH/AChE-IN-1

Names

[ Name ]:
sEH/AChE-IN-1

Biological Activity

[Description]:

sEH/AChE-IN-1 (Compound 12a) is a dual inhibitor of the enzymes soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE). sEH/AChE-IN-1 provides cumulative effects against neuroinflammation and memory impairment. sEH/AChE-IN-1 has the potential for the research of Alzheimer's disease (AD)[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Codony S, et al. Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. J Med Chem. 2022;65(6):4909-4925.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₁ClF₃N₅O₃

[ Molecular Weight ]:
590.04

sEH/AChE-IN-1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds