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1-Methyl-2,6-piperidinedione

Names

[ CAS No. ]:
25077-25-2

[ Name ]:
1-Methyl-2,6-piperidinedione

[Synonym ]:
N-Methylglutarimid
N-Methylglutarimide
Glutarimide,N-methyl
N-methyladipinimide
1-Methylpiperidine-2,6-dione
1-methyl-piperidine-2,6-dione
N-methylglutaramide
2,6-Piperidinedione,1-methyl
2,6-Piperidinedione, 1-methyl-
1-Methylglutarimide
1-Methyl-2,6-piperidinedione

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
243.8±9.0 °C at 760 mmHg

[ Melting Point ]:
30-31°C

[ Molecular Formula ]:
C6H9NO2

[ Molecular Weight ]:
127.141

[ Flash Point ]:
110.7±11.1 °C

[ Exact Mass ]:
127.063332

[ PSA ]:
37.38000

[ LogP ]:
0.35

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.484

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MA5220000
CHEMICAL NAME :
Glutarimide, N-methyl-
CAS REGISTRY NUMBER :
25077-25-2
BEILSTEIN REFERENCE NO. :
0116172
LAST UPDATED :
199710
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C6-H9-N-O2
MOLECULAR WEIGHT :
127.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3400 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - hypermotility, diarrhea
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571226
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>512 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 173,115,1968

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Precursor & DownStream


Related Compounds