4-Chloroindole

Names

[ Name ]:
4-Chloroindole

[Synonym ]:
4-Chloroindole
1H-Indole, 4-chloro-
1H-Indole,4-chloro
EINECS 246-747-8
4-Chloro-1H-indole
Indole,4-chloro
MFCD00005665
4-chloro-indole

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
293.0±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C₈H₆ClN

[ Molecular Weight ]:
151.593

[ Flash Point ]:
158.9±5.4 °C

[ Exact Mass ]:
151.018875

[ PSA ]:
15.79000

[ LogP ]:
2.74

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.688

[ Storage condition ]:
2-8°C

[ Stability ]:
Store in Refrigerator

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

The stability of the nitrosated products of indole, indole-3-acetonitrile, indole-3-carbinol and 4-chloroindole.

Food Chem. Toxicol. 27(11) , 723-30, (1989)

The nitrosation rates of indole-3-acetonitrile, indole-3-carbinol, indole and 4-chloroindole and the stability of their nitrosated products were investigated. Each of the nitrosated indole compounds w...

In-vitro testing and the carcinogenic potential of several nitrosated indole compounds.

Cell Biol. Toxicol. 7(4) , 371-86, (1991)

4-chloro-methoxyindole is a naturally occurring compound in Vicia faba which can easily react with nitrite to form a N-nitroso compound. In this in vitro study, the potential genotoxic effects of nitr...

Expansion of substrate specificity of cytochrome P450 2A6 by random and site-directed mutagenesis.

J. Biol. Chem. 280(49) , 41090-100, (2005)

The natural product indole is a substrate for cytochrome P450 2A6. Mutagenesis of P450 2A6 was done to expand its capability in the oxidization of bulky substituted indole compounds, which are not sub...