Urea,N'-(4-chlorophenyl)-N-methyl-N-nitroso-
Names
[ CAS No. ]:
25355-61-7
[ Name ]:
Urea,N'-(4-chlorophenyl)-N-methyl-N-nitroso-
[Synonym ]:
3-<4-Chlor-phenyl>-1-methyl-1-nitroso-harnstoff
3-(p-Chlorophenyl)-1-methyl-1-nitrosourea
1-Methyl-1-nitroso-3-(p-chlorophenyl)urea
1-(p-Chlorophenyl)-3-methyl-3-nitrosourea
1-(4-chlorophenyl)-3-isopropyl-3-nitrosourea
N-Methyl-N'-(4-chlorophenyl)-N-nitrosourea
N-<4-Chlor-phenyl>-N'-methyl-N'-nitroso-harnstoff
Chemical & Physical Properties
[ Density]:
1.36g/cm3
[ Molecular Formula ]:
C8H8ClN3O2
[ Molecular Weight ]:
213.62100
[ Exact Mass ]:
213.03100
[ PSA ]:
61.77000
[ LogP ]:
2.55810
[ Index of Refraction ]:
1.595
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS6480000
- CHEMICAL NAME :
- Urea, 3-(p-chlorophenyl)-1-methyl-1-nitroso-
- CAS REGISTRY NUMBER :
- 25355-61-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C8-H8-Cl-N3-O2
- MOLECULAR WEIGHT :
- 213.64
- WISWESSER LINE NOTATION :
- ONN1&VMR DG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 598 mg/kg/20W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 634 mg/kg/7W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Gastrointestinal - tumors
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- IAPUDO IARC Publications. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.27- 1979- Volume(issue)/page/year: 31,685,1980
Safety Information
[ HS Code ]:
2924299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%