1,3-Bis(benzyloxycarbonyl)-2-Methyl-2-thiopseudourea
Names
[ CAS No. ]:
25508-20-7
[ Name ]:
1,3-Bis(benzyloxycarbonyl)-2-Methyl-2-thiopseudourea
[Synonym ]:
N,N'-dicarbobenzyloxy-S-methylisothiourea
N,N'-di-Cbz-S-methylisothiourea
SMe(C=NCbz)NHCbz
N,N'-dibenzyloxycarbonyl-S-methylisothiourea
1,3-BIS(BENZYLOXYCARBONYL)-2-METHYL-2-THIOPSEUDOUREA
Z2-S-methylisothiourea
1,3-bis(benzoxycarbonyl)-2-methyl-2-thiopseudo urea
1,3-BIS(BENZYLOXYCARBONYL)-2-METHYL-ISOTHIOUREA
MeSC(=NCBz)NHCbz
MFCD00674040
2-Methyl-1,3-di-Z-isothiourea
Carbamic acid, N,N'-[(E)-(methylthio)methylidyne]bis-, bis(phenylmethyl) ester
Dibenzyl [(E)-(methylsulfanyl)methylylidene]biscarbamate
Dibenzyl [(Z)-(methylthio)methylylidene]biscarbamate
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Melting Point ]:
60-63ºC(lit.)
[ Molecular Formula ]:
C18H18N2O4S
[ Molecular Weight ]:
358.411
[ Exact Mass ]:
358.098724
[ PSA ]:
102.29000
[ LogP ]:
4.58
[ Index of Refraction ]:
1.581
[ Storage condition ]:
2-8℃
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
S22;S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Med. Chem. 50(9) , 2078-88, (2007)
The norepinephrine transporter (NET) substrates [123I]-m-iodobenzylguanidine (MIBG) and [11C]-m-hydroxyephedrine (HED) are used as markers of cardiac sympathetic neurons and adrenergic tumors (pheochr...
Application of molecular topology to the search of novel NSAIDs: experimental validation of activity. Galvez-Llompart M, et al.Lett. Drug Des. Discov. 7(6) , 438-445, (2010)
Total synthesis of (+)-batzelladine A and (-)-batzelladine D, and identification of their target protein.
Chemistry 11(23) , 6878-88, (2005)
Asymmetric total synthesis of batzelladine A (1) and batzelladine D (2) has been achieved. Our synthesis of batzelladines features 1) stereoselective construction of the cyclic guanidine system by mea...