TEAD-IN-2

Names

[ Name ]:
TEAD-IN-2

Biological Activity

[Description]:

TEAD-IN-2 is a novel, orally active inhibitor of transcriptional enhancer associate domain (TEAD) and modulates TEAD by ubiquitination and/or degradation by compounds. TEAD-IN-2 can be used for the research of a variety of diseases, disorders or conditions associated with TEAD[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Stem Cell/Wnt >> YAP

[References]

[1]. Alfredo C. Castro, et al. Preparation of heterocyclic compounds as TEAD degraders and uses thereof. Patent wo2022120355A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₈BrF₃N₂O

[ Molecular Weight ]:
391.23

Related Compounds

TEAD-IN-2
TEAD-IN-3
USP8-IN-2
Chitinase-IN-2 hydrochloride
Telomerase-IN-2
NEP-IN-2
Bis(biotin)
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-(tert-Butoxy)-4-chlorobutane
Tert-butyl methyl(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)azetidin-3-yl)carbamate
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde