Flonoltinib maleate
Names
[ CAS No. ]:
2568842-57-7
[ Name ]:
Flonoltinib maleate
Biological Activity
[Description]:
Flonoltinib maleate is a potent, highly selective, dual JAK2/FLT3 inhibitor with IC50 of 0.8, 1.4, and 15 nM for JAK2, JAK2V617F, and FLT3, respectively.
[References]
1. Hu M, et al. Blood Cancer J. 2022 Mar 7;12(3):37. 2. Zhu J, et al. Biomed Pharmacother. 2021 May;137:111373.
Chemical & Physical Properties
[ Molecular Formula ]:
C29H38FN7O5
[ Molecular Weight ]:
583.665