MEK4 inhibitor 6ff
Names
[ CAS No. ]:
2570386-33-1
[ Name ]:
MEK4 inhibitor 6ff
Biological Activity
[Description]:
MEK4 inhibitor 6ff is potent, selective MEK4 inhibitor with IC50 of 66 nM.MEK4 inhibitor 6ff displays excellent selectivity across the entire MEK family, 150-fold more potent against MEK4 than any other MEKkinase, and is at least 385-fold selective against three other MEK kinases.
[References]
1. Kristine K Deibler, et al. ChemMedChem. 2019 Mar 22;14(6):615-620.
Chemical & Physical Properties
[ Molecular Formula ]:
C14H9FN2O2
[ Molecular Weight ]:
256.236