Acetamide,N-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-
Names
[ CAS No. ]:
2578-75-8
[ Name ]:
Acetamide,N-[5-(5-nitro-2-furanyl)-1,3,4-thiadiazol-2-yl]-
[Synonym ]:
N-acetyl-tiafur
C 132
N-acetyl-thiafur
N-acetyl-furidiazine
Chemical & Physical Properties
[ Density]:
1.605g/cm3
[ Molecular Formula ]:
C8H6N4O4S
[ Molecular Weight ]:
254.22300
[ Exact Mass ]:
254.01100
[ PSA ]:
142.08000
[ LogP ]:
2.26090
[ Index of Refraction ]:
1.66
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AC6500000
- CHEMICAL NAME :
- Acetamide, N-(5-(5-nitro-2-furyl)-1,3,4-thiadiazol-2-yl)-
- CAS REGISTRY NUMBER :
- 2578-75-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C8-H6-N4-O4-S
- MOLECULAR WEIGHT :
- 254.24
- WISWESSER LINE NOTATION :
- T5OJ BNW E- ET5NN DSJ CMV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 33 gm/kg/40W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 gm/kg/46W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors Blood - leukemia
MUTATION DATA
- TYPE OF TEST :
- DNA repair
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 500 nmol/well
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 34,2266,1974 *** REVIEWS *** TOXICOLOGY REVIEW CCSUDL Carcinogenesis--A Comprehensive Survey. (Raven Press, 1185 Ave. of the Americas, New York, NY 10036) V.1- 1976- Volume(issue)/page/year: 4,171,1978
Safety Information
[ HS Code ]:
2934999090
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%