Quinolinium,2-[[[4-[bis(2-chloroethyl)amino]phenyl]imino]methyl]-1-methyl-, chloride (1:1)
Names
[ CAS No. ]:
25843-64-5
[ Name ]:
Quinolinium,2-[[[4-[bis(2-chloroethyl)amino]phenyl]imino]methyl]-1-methyl-, chloride (1:1)
[Synonym ]:
Zimet 3106
Imet 3106
Chemical & Physical Properties
[ Molecular Formula ]:
C21H22Cl3N3
[ Molecular Weight ]:
422.77800
[ Exact Mass ]:
421.08800
[ PSA ]:
19.48000
[ LogP ]:
1.70290
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VC3537000
- CHEMICAL NAME :
- Quinolinium, 2-(N-(p-(bis(2-chloroethyl)amino)phenyl)formimidoyl)- 1-methyl-, chloride
- CAS REGISTRY NUMBER :
- 25843-64-5
- LAST UPDATED :
- 198909
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C21-H22-Cl2-N3.Cl
- MOLECULAR WEIGHT :
- 422.81
- WISWESSER LINE NOTATION :
- T66 BKJ B1 C1UMR DN2G2G &G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 125 mg/kg
- SEX/DURATION :
- female 7-11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year: 110,1067,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 188 mg/kg
- SEX/DURATION :
- female 7-11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year: 110,1067,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 125 mg/kg
- SEX/DURATION :
- female 7-11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,122,1972