Thymidine,5'-deoxy-5'-iodo-

Names

[ Name ]:
Thymidine,5'-deoxy-5'-iodo-

[Synonym ]:
5'-deoxy-5'-iodothymidine
5'-iodo-5'-deoxy-thymidine
5'-Jod-5'-desoxy-thymidin
5'-Deoxy-5'-iodo-D-thymidine

Biological Activity

[Description]:

5′-Deoxy-5′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.871g/cm3

[ Molecular Formula ]:
C₁₀H₁₃IN₂O₄

[ Molecular Weight ]:
352.13

[ Exact Mass ]:
351.99200

[ PSA ]:
84.32000

[ Index of Refraction ]:
1.634

Thymidine,5'-deoxy-5'-iodo-

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds