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Thiazole,2-hydrazinyl-4-(5-nitro-2-furanyl)-

Names

[ CAS No. ]:
26049-68-3

[ Name ]:
Thiazole,2-hydrazinyl-4-(5-nitro-2-furanyl)-

[Synonym ]:
2-Hydrazino-4-(5-nitro-2-furanyl)thiazole
2-Hydrazino-4-(5-nitro-2-furyl)thiazole
2-hydrazino-4-(5-nitrofuran-2-yl)-1,3-thiazole
2-Hydrazino-4-<5-nitro-2-furyl>-thiazol
Thiazole,2-hydrazino-4-(5-nitro-2-furyl)
2-hydrazino-4-(5-nitro-furan-2-yl)-thiazole

Chemical & Physical Properties

[ Density]:
1.631g/cm3

[ Boiling Point ]:
445.5ºC at 760 mmHg

[ Molecular Formula ]:
C7H6N4O3S

[ Molecular Weight ]:
226.21300

[ Flash Point ]:
223.3ºC

[ Exact Mass ]:
226.01600

[ PSA ]:
141.37000

[ LogP ]:
2.24230

[ Vapour Pressure ]:
3.92E-08mmHg at 25°C

[ Index of Refraction ]:
1.718

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ4900000
CHEMICAL NAME :
Thiazole, 2-hydrazino-4-(5-nitro-2-furyl)-
CAS REGISTRY NUMBER :
26049-68-3
LAST UPDATED :
199706
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C7-H6-N4-O3-S
MOLECULAR WEIGHT :
226.23
WISWESSER LINE NOTATION :
T5OJ BNW E- ET5N CSJ BMZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
14 gm/kg/44W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Lungs, Thorax, or Respiration - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
38 gm/kg/46W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors Blood - leukemia
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
21 gm/kg/46W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Skin and Appendages - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
21 gm/kg/46W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :
Phage inhibition capacity
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
100 ug/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 26,3,1974 *** REVIEWS *** TOXICOLOGY REVIEW CCSUDL Carcinogenesis--A Comprehensive Survey. (Raven Press, 1185 Ave. of the Americas, New York, NY 10036) V.1- 1976- Volume(issue)/page/year: 4,171,1978

Synthetic Route

Precursor & DownStream


Related Compounds