N-Trifluoroacetyldoxorubicin
Names
[ CAS No. ]:
26295-56-7
[ Name ]:
N-Trifluoroacetyldoxorubicin
[Synonym ]:
5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-.α.-L-lyxo-hexopyranosyl]oxy]-, (8S-cis)-
Chemical & Physical Properties
[ Density]:
1.66g/cm3
[ Boiling Point ]:
855.4ºC at 760 mmHg
[ Molecular Formula ]:
C29H28F3NO12
[ Molecular Weight ]:
639.52700
[ Flash Point ]:
471.1ºC
[ Exact Mass ]:
639.15600
[ PSA ]:
209.15000
[ LogP ]:
1.11200
[ Vapour Pressure ]:
3.7E-31mmHg at 25°C
[ Index of Refraction ]:
1.656
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QI9428000
- CHEMICAL NAME :
- 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-8-(hydroxyacetyl)-1-methoxy-10-(( 2,3,6-trideoxy- 3-(trifluoroacetamido)-alpha-L-lyxo-hexopyranosyl)oxy )-6,8,11-trihydroxy-, (8S-cis)-
- CAS REGISTRY NUMBER :
- 26295-56-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C29-H28-F3-N-O12
- MOLECULAR WEIGHT :
- 639.58
- WISWESSER LINE NOTATION :
- L E6 C666 BV MVT&&&J DQ HV1Q HQ KQ RO1 FO- FT6OTJ B1 CQ DMVXFFF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 9 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 41,1006,1981