1H-Pyrrolizine-7-methanol,2,3-dihydro-1-hydroxy-, (1S)-
Names
[ CAS No. ]:
26400-24-8
[ Name ]:
1H-Pyrrolizine-7-methanol,2,3-dihydro-1-hydroxy-, (1S)-
[Synonym ]:
Dehydroheliotridin
3,8a-Didehydroheliotridine
Heliotridine,8-didehydro
dehydroheliotridine
3,8-Dehydroheliotridine
Chemical & Physical Properties
[ Density]:
1.39g/cm3
[ Boiling Point ]:
361.2ºC at 760 mmHg
[ Molecular Formula ]:
C8H11NO2
[ Molecular Weight ]:
153.17800
[ Flash Point ]:
172.3ºC
[ Exact Mass ]:
153.07900
[ PSA ]:
45.39000
[ LogP ]:
0.41750
[ Vapour Pressure ]:
7.54E-06mmHg at 25°C
[ Index of Refraction ]:
1.65
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UY8350000
- CHEMICAL NAME :
- 1H-Pyrrolizine-7-methanol, 2,3-dihydro-1-hydroxy-, (S)-
- CAS REGISTRY NUMBER :
- 26400-24-8
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C8-H11-N-O2
- MOLECULAR WEIGHT :
- 153.20
- WISWESSER LINE NOTATION :
- T55 AN&TJ D1Q FQ -S
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 92 mg/kg
- TOXIC EFFECTS :
- Liver - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 40 mg/kg
- SEX/DURATION :
- female 14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 60 mg/kg
- SEX/DURATION :
- female 14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 30 mg/kg
- SEX/DURATION :
- female 14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 40 mg/kg
- SEX/DURATION :
- female 14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Mammal - species unspecified Leukocyte
- DOSE/DURATION :
- 500 nmol/L
- REFERENCE :
- CYTBAI Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969- Volume(issue)/page/year: 3,245,1971
Safety Information
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%