Glyceryl monocaprate

Names

[ Name ]:
Glyceryl monocaprate

[Synonym ]:
1-Monodecanoyl Glycerol
EINECS 247-667-6
Glycerol α-Monodecanoate
2,3-Dihydroxypropyl decanoate
MFCD00056656

Biological Activity

[Description]:

Glyceryl monocaprate (Monolaurin) is a 1-monoglyceride of capric acid against gram-positive bacterial infections[1]. Glyceryl monocaprate (Monolaurin) has inhibitory effect on Herpes Simplex Virus (HSV) and offers an effective treatment for herpes labialiss[2].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HSV

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

IC50: Gram-positive Bacterial; HSV[1][2]

[In Vitro]

Glyceryl monocaprate (Monolaurin) has an antimicrobial activity against gram-positive ATCC SA 29123[1].

[In Vivo]

Glyceryl monocaprate (Monolaurin) combines with low-dose doxycycline offers an effective treatment for herpes labialiss, significantly reducing time to healing and pain compared with the placebo and monocaprin alone[2].

[References]

[1]. Chan WY, et al. In vitro antimicrobial activity of seven adjuvants against common pathogens associated with canine otitis externa.Vet Dermatol. 2019 Apr;30(2):133-e38.

[2]. Skulason S, et al. A study of the clinical activity of a gel combining monocaprin and doxycycline: a novel treatment for herpes labialis.J Oral Pathol Med. 2012 Jan;41(1):61-7.

Chemical & Physical Properties

[ Density]:
1.017 g/cm3

[ Melting Point ]:
53ºC

[ Molecular Formula ]:
C₁₃H₂₆O₄

[ Molecular Weight ]:
246.34300

[ Flash Point ]:
129.6ºC

[ Exact Mass ]:
246.18300

[ PSA ]:
66.76000

[ LogP ]:
2.02350

[ Vapour Pressure ]:
5.96E-07mmHg at 25°C

[ Index of Refraction ]:
1.466

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ WGK Germany ]:
1