sorbitan tristearate

Names

[ Name ]:
sorbitan tristearate

[Synonym ]:
Glycomul(R) TS KFG
SPAN 65
EmulsifierS65
SPAN(R) 65
SPAN(TM) 65
Lonzest(R) STS
Sorbitantristearat
EMALEX EG-2854-S
MFCD00151165
EINECS 247-891-4

Biological Activity

[Description]:

Sorbitan tristearate is a non-ionic surfactant, with a synergistic effect on skin permeability. Sorbitan tristearate can be used as an excipient, such as emulsifier. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Karande P, et al. Synergistic effects of chemical enhancers on skin permeability: a case study of sodium lauroylsarcosinate and sorbitan monolaurate[J]. European journal of pharmaceutical sciences, 2007, 31(1): 1-7.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Chemical & Physical Properties

[ Density]:
0.96 g/cm3

[ Boiling Point ]:
885.4ºC at 760 mmHg

[ Molecular Formula ]:
C₆₀H₁₁₄O₈

[ Molecular Weight ]:
963.54200

[ Flash Point ]:
150 °C

[ Exact Mass ]:
962.85100

[ PSA ]:
108.36000

[ LogP ]:
17.89740

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.478

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1