N4-Benzoylcytosine

Names

[ Name ]:
N4-Benzoylcytosine

[Synonym ]:
N-(2-oxohydropyrimidin-4-yl)benzamide
N4-Benzoylcytosine
N6-benzoylcytosine
N3-benzoylcytosine
N-(2-Oxo-1,2-dihydro-4-pyrimidinyl)benzamide
N-(2-Oxo-1,2-dihydropyrimidin-4-yl)benzamide
MFCD00239434
N-(1,2-dihydro-2-oxopyrimidin-4-yl)-benzamide
N4-Benzoyl Cytosine
N-benzoylcytosine
Benzamide, N-(1,2-dihydro-2-oxo-4-pyrimidinyl)-
N-(2-Oxo-2,3-dihydropyrimidin-4-yl)benzamide
N4-Bz-cytosine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
>300 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₁H₉N₃O₂

[ Molecular Weight ]:
215.208

[ Exact Mass ]:
215.069473

[ PSA ]:
74.85000

[ LogP ]:
0.42

[ Index of Refraction ]:
1.652

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R20/22;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Synthesis and biological evaluation of 3'-C-ethynyl and 3'-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides.

Med. Chem. 8(3) , 320-9, (2012)

A novel series of 3'-C-ethynyl and 3'-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides has been designed and synthesized. Reaction of 3-keto glucoside 1 with ethynyl magnesium brom...

Nucleosides and nucleotides. 232. Synthesis of 2'-C-methyl-4'-thiocytidine: unexpected anomerization of the 2'-keto-4'-thionucleoside precursor.

Nucleosides Nucleotides Nucleic Acids 24(10-12) , 1789-800, (2005)

The synthesis of 2'-C-methyl-4'-thiocytidine (16) is described. Since the 2'-keto-4'-thiocytidine derivative 2beta unexpectedly isomerized to 2alpha and the methylation of 2beta proceeded predominantl...

Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2', 3'-unsaturated L-nucleosides.

J. Med. Chem. 42(7) , 1320-8, (1999)

The synthesis of L-nucleoside analogues containing 2'-vinylic fluoride was accomplished by direct condensation method, and their anti-HIV and anti-HBV activities were evaluated in vitro. The key inter...