Reomol DiDP

Names

[ Name ]:
Reomol DiDP

[Synonym ]:
Bisisocyanide
EINECS 247-977-1
Isodecyl Alcohol Phthalate (2:1)
di-iso-decyl phthalate
1,2-Benzenedicarboxylic acid diisodecyl ester
bis(8-methylnonyl) benzene-1,2-dicarboxylate
Plasthall DIDP
Diisodecyl Phthalate
Bis(8-methylnonyl) phthalate
Di-isodecyl phthalate
Reomol DiDP
1,2-Benzenedicarboxylic acid, bis(8-methylnonyl) ester
Jayflex DIDP
15,16-dihydrocyclopenta<a>phenanthren-3,4,17-trione 17-methoxime
Sansocizer DIDP
diisocyanogen
Phthalic Acid Diisodecyl Ester
MFCD00048389
ISODECYL PHTHALATE
Phthalic Acid Bis(8-methylnonyl) Ester
15,16-Seco-serratan-15,16-disaeure-dimethylester
Hexaplas DIDP

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
425.8±13.0 °C at 760 mmHg

[ Melting Point ]:
235ºC

[ Molecular Formula ]:
C₂₈H₄₆O₄

[ Molecular Weight ]:
446.662

[ Flash Point ]:
227.6±9.3 °C

[ Exact Mass ]:
446.339600

[ PSA ]:
52.60000

[ LogP ]:
10.83

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.487

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TI1270000

CHEMICAL NAME :: Phthalic acid, diisodecyl ester

CAS REGISTRY NUMBER :: 26761-40-0

LAST UPDATED :: 199806

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C28-H46-O4

MOLECULAR WEIGHT :: 446.74

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 64 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 3,131,1973

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >130 mg/m3/6H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001)

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >130 mg/m3/6H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001)

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 22500 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 3,61,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >3160 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001)

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >130 mg/m3/6H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001) ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 58800 mg/kg/14W-C

TOXIC EFFECTS :: Liver - changes in liver weight

REFERENCE :: EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 3,131,1973 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 10 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 35,501,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-SWEDEN:TWA 3 mg/m3;STEL 5 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83278 No. of Facilities: 1017 (estimated) No. of Industries: 18 No. of Occupations: 41 No. of Employees: 21856 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83278 No. of Facilities: 2962 (estimated) No. of Industries: 53 No. of Occupations: 57 No. of Employees: 80441 (estimated) No. of Female Employees: 31734 (estimated)

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H410

[ Precautionary Statements ]:
P273-P501

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
23-24/25

[ RIDADR ]:
UN 3082 9 / PGIII

[ WGK Germany ]:
1

[ RTECS ]:
TI1270000

[ HS Code ]:
2917349000

Customs

[ HS Code ]: 2917349000

[ Summary ]:
2917349000 other esters of orthophthalic acid。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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Effects of phthalates on the human corneal endothelial cell line B4G12.

Int. J. Toxicol. 31(4) , 364-71, (2012)

Phthalates are industrial chemicals used in many cosmetics. We evaluated an in vitro model for eye irritancy testing using the human corneal endothelial cell line B4G12. Cell proliferation and toxicit...