ER-001259851-000
Names
[ CAS No. ]:
2685738-33-2
[ Name ]:
ER-001259851-000
Biological Activity
[Description]:
ER-001259851-000 is a potent, selective, orally active Axl inhibitor with IC50 of 5.2 nM in cell free assays, displays >35-fold selectivity against Mer (IC50=190 nM).ER-001259851-000 shows a promising pharmacokinetic profile in mice.
[References]
1. Satoshi Inoue, et al. Bioorg Med Chem Lett. 2021 Sep 15;48:128247.
Chemical & Physical Properties
[ Molecular Formula ]:
C36H41FN8O4
[ Molecular Weight ]:
668.774