rac AMphetaMine Hydrochloride
Names
[ CAS No. ]:
2706-50-5
[ Name ]:
rac AMphetaMine Hydrochloride
[Synonym ]:
1-methyl-2-phenylethylammonium chloride
1-phenyl-2-propylamine hydrochloride
(+/-)-Amphetamine hydrochloride
Amphetaminhydrochlorid
phenamine hydrochloride
1-Phenyl-2-propyl methanesulfonate
1-methyl-2-phenylethyl methanesulfonate
1-methyl-2-phenyl-ethylamine hydrochloride
1-phenyl-2-propanol mesylate
Chemical & Physical Properties
[ Boiling Point ]:
201.5ºC at 760mmHg
[ Melting Point ]:
127-129?C
[ Molecular Formula ]:
C9H14ClN
[ Molecular Weight ]:
171.66700
[ Flash Point ]:
87.4ºC
[ Exact Mass ]:
171.08100
[ PSA ]:
26.02000
[ LogP ]:
3.07860
[ Storage condition ]:
Controlled Substance, -20?C Freezer, Under Inert Atmosphere
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH9798450
- CHEMICAL NAME :
- Phenethylamine, alpha-methyl-, hydrochloride, (+-)-
- CAS REGISTRY NUMBER :
- 2706-50-5
- LAST UPDATED :
- 198806
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C9-H13-N.Cl-H
- MOLECULAR WEIGHT :
- 171.69
- WISWESSER LINE NOTATION :
- ZY1&1R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 45 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 64,533,1942
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Vascular - BP elevation not characterized in autonomic section
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,100,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,187,1943
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 52 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,339,1933
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300
[ Precautionary Statements ]:
P264-P301 + P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T
[ Risk Phrases ]:
25
[ Safety Phrases ]:
45
[ RIDADR ]:
UN 2811 6.1 / PGII
[ RTECS ]:
SH9798450
[ HS Code ]:
2921499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921499090
[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%