2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one

Names

[ Name ]:
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one

[Synonym ]:
2-Amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-on
2-AMIO-6-METHYL-4-PROPYL-4H-[1,2,4] TRIAZOLO[1,5-A]PYRIMIDIN-5-ONE
1,2,4Triazolo1,5-apyrimidin-5(4H)-one,2-amino-6-methyl-4-propyl
PP-796 emetic
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one
2-AMINO-6-METHYL-4-PROPYL-4H-[1,2,4]TRIAZOLO-[1,5-A]PYRIMIDIN-5-ONE
EINECS 248-383-5
MFCD06407961
AMINOPROPYLTRIAZOLOPYRIMIDONE
2-azanyl-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
2-amino-6-methyl-5-oxo-4-n-propyl-4,5-dihydro-s-triazolo [1,5-a] pyrimidine

Chemical & Physical Properties

[ Density]:
1.44g/cm3

[ Boiling Point ]:
459.9ºC at 760 mmHg

[ Melting Point ]:
161.8-163ºC

[ Molecular Formula ]:
C₉H₁₃N₅O

[ Molecular Weight ]:
207.23200

[ Flash Point ]:
231.9ºC

[ Exact Mass ]:
207.11200

[ PSA ]:
78.21000

[ LogP ]:
0.77280

[ Vapour Pressure ]:
1.22E-08mmHg at 25°C

[ Index of Refraction ]:
1.696

[ Storage condition ]:
Store at +4°C

[ Water Solubility ]:
DMSO: 13 mg/mL

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
UN 2811

[ WGK Germany ]:
1

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Characteristic behavioural alterations in rats induced by rolipram and other selective adenosine cyclic 3', 5'-monophosphate phosphodiesterase inhibitors.

Psychopharmacology 77(4) , 309-16, (1982)

The significance of a characteristic symptomatology (hypothermia, hypoactivity, forepaw shaking, grooming, head twitches) as a potential in vivo correlate of enhanced availability of brain adenosine c...

Rolipram, a novel antidepressant drug, reverses the hypothermia and hypokinesia of monoamine-depleted mice by an action beyond postsynaptic monoamine receptors.

Neuropharmacology 25(10) , 1119-26, (1986)

The antidepressant potential of rolipram and inhibitors of phosphodiesterase (PDE) which are selective for cyclic AMP has previously been ascribed to enhancement of central noradrenergic transmission ...

Effects of isoprenaline, levodopa and a phosphodiesterase inhibitor (ICI 63,197) on cyclic AMP levels and contractions of soleus muscles in anesthetized cats.

Clin. Exp. Pharmacol. Physiol. 8(1) , 57-66, (1981)

1. Cyclic AMP levels have been determined in the soleus muscles of anaesthetized cats in the absence of drugs, and during depression of incomplete tetanic contractions produced by (-)-isoprenaline, IC...