ALPK1-IN-1

ALPK1-IN-1 (Compound A001) is a potent inhibitor of alpha-kinase 1 (ALPK1). ALPK1 is an intracytoplasmic serine threonine protein kinase that plays an important role in activating the innate immune response to bacteria via TRAF-interacting protein with forkhead-associated domain (TIFA) dependent proinflammatory NF-κB signaling[1].

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

[1]. Danyang Liu, et al. Alpha protein kinase 1 inhibitors and methods of use. WO2022063152A1.