MRV03-070

Names

[ Name ]:
MRV03-070

Biological Activity

[Description]:

MRV03-070 is an inhibitor of colibactin-activating peptidase ClbP with an IC50 value of 69 nM, acts like biosynthetic precursor precolibactin[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

MRV03-070 (compound 4) (0.01 nM-0.1 mM for 1 h) inhibits ClbP acitivity with IC50s of 69 nM and 27 nM, respectively, measured both in vitro and in E. coli BL21 overexpressing ClbP[1].

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₃BN₂O₄

[ Molecular Weight ]:
236.03

Related Compounds

MRV03-069
MRV03-037
AMD-070 hydrochloride
(Z)-6-[(2S,4R)-4-[(4-chlorophenyl)sulfonylamino]-1-(pyridin-3-ylmethyl)pyrrolidin-2-yl]hex-5-enoic acid,hydrochloride
TAK-070
AMD-070
2-Hydroxy-7-(trifluoromethyl)-4H-pyrido[1,2-A]pyrimidin-4-one
2-cyclopropyl-2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4,4-trifluorobutanamido]oxy}acetic acid
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-amino-3-(4-methanesulfonyl-1H-pyrazol-1-yl)propanenitrile
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde