azaperol

Names

[ Name ]:
azaperol

[Synonym ]:
1-(4-Fluorphenyl)-4-<4-(2-pyridyl)piperazino>butan-1-ol
1-(4-fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-ol
Azaperol
|A-(4-Fluorophenyl)-4-(2-pyridinyl)-1-piperazinebutanol

Chemical & Physical Properties

[ Density]:
1.177g/cm3

[ Boiling Point ]:
501.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₉H₂₄FN₃O

[ Molecular Weight ]:
329.41200

[ Flash Point ]:
257.2ºC

[ Exact Mass ]:
329.19000

[ PSA ]:
39.60000

[ LogP ]:
2.85940

[ Vapour Pressure ]:
6.95E-11mmHg at 25°C

[ Index of Refraction ]:
1.577

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ Safety Phrases ]:
6-20-62

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
29335990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Simultaneous determination of azaperone and azaperol in animal tissues by HPLC with confirmation by electrospray ionization mass spectrometry

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877(3) , 166-72, (2009)

A simple method is described for the determination of azaperone and its metabolite, azaperol, in animal tissues by high-performance liquid chromatography with ultraviolet detection (HPLC/UV). Chromato...

Gas chromatographic-mass spectrometric analysis of veterinary tranquillizers in urine: evaluation of method performance.

J. Chromatogr. B. Biomed. Sci. Appl. 734(1) , 113-20, (1999)

A method for analysis of veterinary tranquillizers in urine using gas chromatography-mass spectrometry (GC-MS) is described. Detection limits are 5 microg/l for ketamine, azaperone and the phenothiazi...

Evaluation of the effects of the enantiomers of reduced haloperidol, azaperol, and related 4-amino-1-arylbutanols on dopamine and sigma receptors.

J. Med. Chem. 36(24) , 3929-36, (1993)

The enantiomers of reduced haloperidol (3a), azaperol (3b), and the related compound BMY-14802 (3c) were prepared in high optical purity. The affinity of these compounds for dopamine D2 and D3 recepto...