Pregna-3,5-diene-6-carboxaldehyde,21-(acetyloxy)-3-(2-chloroethoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-20-oxo-,(11b,16a)-
Names
[ CAS No. ]:
2825-60-7
[ Name ]:
Pregna-3,5-diene-6-carboxaldehyde,21-(acetyloxy)-3-(2-chloroethoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-20-oxo-,(11b,16a)-
[Synonym ]:
Cortocin F
DeflaMin
Fluoroformylon
Fluderma
Cutisterol
FluoforMylon
FI-6341
Deflamene
formocortal
Chemical & Physical Properties
[ Density]:
1.33g/cm3
[ Boiling Point ]:
683.7ºC at 760mmHg
[ Molecular Formula ]:
C29H38ClFO8
[ Molecular Weight ]:
569.05900
[ Flash Point ]:
367.3ºC
[ Exact Mass ]:
568.22400
[ PSA ]:
108.36000
[ LogP ]:
3.96280
[ Vapour Pressure ]:
1.21E-21mmHg at 25°C
[ Index of Refraction ]:
1.564
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU3460000
- CHEMICAL NAME :
- Pregna-3,5-diene-6-carboxaldehyde, 3-(2-chloroethoxy)-9-fluoro-11-beta,16-alpha,17,21- tetrahydroxy-20-oxo-, cyclic 16,17-acetal with acetone, 21-acetate
- CAS REGISTRY NUMBER :
- 2825-60-7
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C29-H38-Cl-F-O8
- MOLECULAR WEIGHT :
- 569.12
- WISWESSER LINE NOTATION :
- T F5 E5 B666 GO IO OU QUTJ A1 BF CQ E1 FV1OV1 H1 H1 OVH RO2G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 537 mg/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 4,88,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 490 mg/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 4,88,1971