N-Methylolchloroacetamide

Names

[ Name ]:
N-Methylolchloroacetamide

[Synonym ]:
N-hydroxymethylchloroacetamide
EINECS 220-598-9
Chloracetamide-N-metholol
Caswell No. 192BB
N-hydroxymethylchloroacetic amide
N-Methylolchloroacetamide
Grota
N-methylol-chloracetamide
Acetamide, 2-chloro-N-(hydroxymethyl)-
2-Chloro-N-(hydroxymethyl)acetamide
N-hydroxymethyl-chloroacetamide
Grotan DF-35
Chloracetamide-N-methanol
MFCD00021961

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
374.0±27.0 °C at 760 mmHg

[ Melting Point ]:
100-105 °C(lit.)

[ Molecular Formula ]:
C₃H₆ClNO₂

[ Molecular Weight ]:
123.538

[ Flash Point ]:
180.0±23.7 °C

[ Exact Mass ]:
123.008705

[ PSA ]:
49.33000

[ LogP ]:
-1.32

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.471

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB5733000

CHEMICAL NAME :: Acetamide, 2-chloro-N-hydroxymethyl-

CAS REGISTRY NUMBER :: 2832-19-1

BEILSTEIN REFERENCE NO. :: 1811765

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C3-H6-Cl-N-O2

MOLECULAR WEIGHT :: 123.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 144 mg/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 156,19,1985 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R20/21/22;R34;R40;R43

[ Safety Phrases ]:
S26-S27-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
AB5733000

[ HS Code ]:
2921199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Formaldehyde-releasers: relationship to formaldehyde contact allergy. Part 2: Metalworking fluids and remainder.

Contact Dermatitis 63(3) , 129-39, (2010)

We have reviewed formaldehyde-releasers used in metalworking fluids (MWFs) in this and a previous part of a two-part article. These biocides do not appear to be frequent or important sensitizers. Even...

Formaldehyde-releasers: relationship to formaldehyde contact allergy. Contact allergy to formaldehyde and inventory of formaldehyde-releasers.

Contact Dermatitis 61(2) , 63-85, (2009)

This is one of series of review articles on formaldehyde and formaldehyde-releasers (others: formaldehyde in cosmetics, in clothes and in metalworking fluids and miscellaneous). Thirty-five chemicals ...

Effect of Prolonged Repeated Exposure to Formaldehyde Donors with Doses Below the EC3 Value on Draining Lymph Node Responses.

J. Immunotoxicol. 4(3) , 239-46, (2007)

In the Local Lymph Node Assay (LLNA), a stimulation index of 3 (SI = 3) is established as a threshold value for hazard identification of sensitization. The corresponding EC3 value, the effective conce...