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4-ACETAMIDOFLUORENE

Names

[ CAS No. ]:
28322-02-3

[ Name ]:
4-ACETAMIDOFLUORENE

[Synonym ]:
2-acetylaminofluorene
N-(9H-fluoren-4-yl)acetamide
N-Fluoren-4-ylacetamide
Acetamide,N-fluoren-4-yl
4-Fluorenylacetamide
4-ACETYLAMINOFLUORENE
N-Fluoren-4-yl-acetamid
N-4-Fluorenylacetamide
4-Acetamidofluorene
4-AAF
Acetamide,N-9H-fluoren-4-yl
N-9H-Fluoren-4-ylacetamide

Chemical & Physical Properties

[ Density]:
1.23g/cm3

[ Boiling Point ]:
463.1ºC at 760mmHg

[ Melting Point ]:
198-200ºC

[ Molecular Formula ]:
C15H13NO

[ Molecular Weight ]:
223.27000

[ Flash Point ]:
277.2ºC

[ Exact Mass ]:
223.10000

[ PSA ]:
29.10000

[ LogP ]:
3.28920

[ Vapour Pressure ]:
9.3E-09mmHg at 25°C

[ Index of Refraction ]:
1.673

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB9530000
CHEMICAL NAME :
Acetamide, N-fluoren-4-yl-
CAS REGISTRY NUMBER :
28322-02-3
BEILSTEIN REFERENCE NO. :
2975269
LAST UPDATED :
199612
DATA ITEMS CITED :
25
MOLECULAR FORMULA :
C15-H13-N-O
MOLECULAR WEIGHT :
223.29
WISWESSER LINE NOTATION :
L B656 HHJ CMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
364 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4175 mg/kg/17W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5240 mg/kg/57W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - uterine tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6300 mg/kg/30W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Endocrine - tumors
TYPE OF TEST :
DNA repair

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Kidney
DOSE/DURATION :
25 mg/L
REFERENCE :
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,638,1981

Safety Information

[ Risk Phrases ]:
23/24/25-46

[ RIDADR ]:
UN 2811

[ HS Code ]:
2924299090

Synthetic Route

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds